|
KMID : 1005220150300030143
|
|
Journal of Embryo Transfer
2015 Volume.30 No. 3 p.143 ~ p.147
|
|
|
Association with Post-Thawed Semen Motility and Kinematic Characteristics of g.35756 T>C on Estrogen Receptor 1 (ESR1) Gene in Duroc Pigs
|
|
Cho Eun-Seok
Kim Ki-Hyun
Woo Jae-Seok
Lee Mi-Jin
Ko Jun-Ho
Kim Young-Ju
Sa Soo-Jin
|
|
|
Abstract
|
|
|
|
Cryopreservation of boar semen is continually researched in reproductive technologies and genetic resource banking in breed conservation. For evaluating the boar semen quality, sperm motility (MOT) is an important parameter because the movement of spermatozoa indicates active metabolism, membrane integrity and fertilizing capacity. Various researches have been trying to improve the quality of semen Post-thawed in boar. Recently, polymorphism (g. 35756 T>C) of Estrogen Receptor 1 (ESR1) gene reported to be significant association with MOT. This study was conducted to evaluate the ESR1 gene as a positional controlling for motility and kinematic characteristics of post-thawed boar semen. To results, The g.35756 T>C SNP of ESR1 was significantly associated with frozen semen motility and kinematic characteristics. The g.35756 T>C SNP was high significantly associated with MOT, VCL, VSL and VAP (p<0.001). The SNP was also significantly associated with ALH (P<0.05). Therefore, we suggest that the g. 35756 T>C polymorphism in the intron 1 region of the porcine ESR1 gene could potentially be applied in frozen semen programs to improve MOT trait, but only after validation in other populations.
|
|
|
KEYWORD
|
|
|
estrogen receptor 1 , boar semen quality , polymorphism
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|